How Is Juvéderm® ULTRA Different? 

• Lasting results
• Smoother injection and results
• The most comfortable treatment experience possible
• The Juvéderm^® ULTRA range of products vs. wrinkle-relaxing treatments
• The Juvéderm^® ULTRA range of products vs. collagen fillers
• The Juvéderm^® ULTRA range of products vs. other hyaluronic acid (HA) fillers

Lasting results with Juvéderm^® ULTRA

In a study carried out in the US, 292 patients were given Juvéderm^® ULTRA or ULTRA PLUS wrinkle injection in one nose to mouth line, and a collagen filler in the other. Collagen fillers are often used for studies where the investigators are trying to see differences in how well they work.

The results of this study showed that 81 percent of patients treated with Juvéderm^® ULTRA Plus wrinkle treatment (equivalent of Juvéderm^® ULTRA 3) still had a significant improvement in treated wrinkle severity after 9 months; 78 percent still showed improvement at over 1 year. This was the data used to secure US Food and Drug Administration (US FDA) approval of the claim that the Juvéderm^® family of products last up to 1 year. See the results below.

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Smoother wrinkle injection and results

The Juvéderm^® ULTRA range of products was developed to be smoother than most hyaluronic acid (HA) dermal filler treatments, meaning that it is easy to inject and gives a very natural look and feel once it is in the skin. In fact…you can see the difference.

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The most comfortable dermal filler treatment experience possible

Possibly the biggest difference between the Juvéderm^® ULTRA range of products and other fillers is the comfort level our patients experience. When we asked people undergoing treatment what they wanted most, and medical aesthetic practitioners how we could best improve the dermal filler experience, both groups agreed that achieving the most the comfortable wrinkle injection experience possible was a key consideration. We at Allergan listened to this feedback and enhanced the Juvéderm^® ULTRA range of products with an anaesthetic commonly used by dentists and doctors for local numbing.

Juvéderm^® ULTRA Expert Evaluation - part 1

A study carried out in late 2007 by Dr Phillip Levy, a dermatologist from Geneva, Switzerland, Dr Koenraad de Boulle, a dermatologist from Aalst in Belgium and Dr Herve Raspaldo, a plastic surgeon from Nice, France, compared Juvéderm^® ULTRA 3 to another hyaluronic acid (HA) dermal filler on the market (Surgiderm 30 XP). The study demonstrated that Juvéderm^® ULTRA 3 was considered very easy or easy to inject in 95 percent of dermal filler treatments. There was a statistically significant reduction in pain when using Juvéderm^® ULTRA 3 compared to the other dermal fillers proving that Juvéderm^® ULTRA increased patient comfort during the injections and overall improved experience.

Juvéderm^®ULTRA Expert Evaluation – part 2

A similar, broader study followed, when 806 patients were treated by 82 different practitioners. All the participants in the trial had previously had a different hyaluronic acid (HA) filler treatment and they were asked to compare the previous treatment experience with Juvéderm^® ULTRA 3. More than 80 percent of participants and practitioners thought Juvéderm^® ULTRA 3 was less painful than other hyaluronic acid dermal filler treatments. More than 97 percent would recommend wrinkle filler treatment with Juvéderm^® ULTRA 3 to friends, family or colleagues.

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What's the difference between Juvéderm^® ULTRA and wrinkle-relaxing treatments?

The Juvéderm^® ULTRA range of products and wrinkle-relaxing treatments (botulinum toxin type A) work in different ways.

The Juvéderm^® ULTRA range of products mimics the hydrating and lifting effect of your skin’s natural hyaluronic acid (HA), which keeps the skin hydrated and elastic. It fills in and smoothes away facial lines and acne scars, other skin contour deficiencies, and lost volume. The most appropriate lines to treat with the Juvéderm^® ULTRA range of products are those that are described as static—this means the deep facial lines you can see when your face is still. Static lines are due to lack of elasticity of the skin caused by sun damage, smoking, and unfortunately genetics. Wrinkle-relaxing treatments work in a targeted way to relax the tiny muscles that cause frown lines, smoothing out wrinkles for 4 months or longer.

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What's the difference between the Juvéderm^® ULTRA range of products and collagen injections?

Juvéderm^® ULTRA is made of a substance called hyaluronic acid (HA), which is found naturally in the skin, alongside collagen. These two components of skin, along with some others, tend to break down over time, letting the tell tale signs of ageing show.

Collagen injections have been used for some time as dermal fillers to fill out the loss of skin volume, removing wrinkles and restoring volume to the face. HA fillers, such as the Juvéderm^® ULTRA range of products have now become more popular because they last longer—in the case of the Juvéderm^® family, up to 1 year whereas most collagen injections tended to wear off after around 4 months.

Because they play different roles in restoring your skin's natural look, the Juvéderm^® ULTRA range of products may be used in combination with collagen to create the results you want. It should be noted, however, that they cannot be used to treat the same lines at the same time.

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How does the Juvéderm^® ULTRA range of products compare with other hyaluronic acid (HA) fillers on the market?

A study carried out by Dr Levy, Dr De Boulle and Dr Raspaldo compared a different HA filler (a product called Restylane—Perlane, made by QMed) to Juvéderm^® ULTRA 3. In total they treated 126 patients, using Juvéderm^® ULTRA 3 in one nose to mouth line, and Perlane in the other. The practitioners were advised to use enough product to get the aesthetic effect they were happy with and the same volume was used with both products (0.6 mL per side).

The study concluded that Juvéderm^® ULTRA 3 provided a superior comfort during the whole wrinkle injection experience compared with Perlane and had equivalent aesthetic outcomes. When asked which product they preferred, a massive 95 percent of patients preferred the side with Juvéderm^® ULTRA 3 showing that this really is a patient-friendly treatment!

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